Dr. Eliahu Hershkovitz
Thesis Name :SYN - TETRAHYDROBIMANES & BIMANES
This thesis was submitted to the senate of Tel Aviv University in 09/ 1990.
This work was carried under the supervision of Prof. E.M Kosower in the School of Chemistry Tel- Aviv, Israel
The goal of this work was to find additional routes for the preparation of new bimanes.
Moving along this road leads to a new family of gamma lactams which is the reduced form of bimanes, 1,5- diazabicyclo[3.3.0.]octa-2,8-dione, syn-tetrahydrobimane (syn-THB).
It was found that a substituted syn-THB has anti-bacterial activity (pages 11-15,99)
Syn-THB showed also encouraging results as a nootropic agent (pages 8-10, 96-98)
I went on an exciting journey 27 years ago waiting for someone to continue the research
synTHB may be a lead compound for new drugs in both fields psycho- active and anti-bacterial drugs.
Please let me know if you wish to explore the therapeutic potential of synTHB.
Dr. Eliahu Hershkovitz
Link to my thesis: https://drive.google.com/drive/folders/1PSfHrfb-Mr07peVvG3H3O0GMgKhIts2_?usp=sharing
tetrahydro bimanes ; nootropic ; gaba lactam ; maze ; anti microbiotical,rod-like polymer